Article indentifying kinesin KIF14 as a new regulator of cilia formation and function

Posted on May 5, 2020 by Lukáš Čajánek

Study led by Petra Pejšková from a group of Lukas Cajanek, entitled: KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling has been accepted for publication in Journal of Cell Biology. This work shows for the first time kinesin KIF14 localizes to primary cilia and is required for its correct formation – cilia form at reduced rate Read more about Article indentifying kinesin KIF14 as a new regulator of cilia formation and function[…]

Publication on identification and characterisation of TTBK2-driven phosphorylations during ciliogenesis

Posted on April 7, 2020April 29, 2020 by Lukáš Čajánek

Study led by Ondrej Bernatik from a group of Lukas Cajanek, entitled: Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2 has been accepted for publication in Mol Biol Cell. This work identifies several novel substrates and many new target sites of TTBK2 and hence provides valuable insight into the molecular control of Read more about Publication on identification and characterisation of TTBK2-driven phosphorylations during ciliogenesis[…]

Article on the links between centrosome and pluripotency

Posted on September 26, 2018 by Lukáš Čajánek

Study led by Tereza Renzova from a group of Lukas Cajanek, entitled: Inactivation of PLK4-STIL Module Prevents Self-Renewal and Triggers p53-Dependent Differentiation in Human Pluripotent Stem Cells has been accepted for publication in Stem Cell Reports. The work has also been recently featured at Science Trends.

PhD students wanted !

Posted on January 26, 2018January 26, 2018 by Lukáš Čajánek

Open PhD positions in Cajanek group and Bohaciakova group .

Review on centrosomes, cell cycle, and Wnt signaling

Posted on August 8, 2017August 8, 2017 by Lukáš Čajánek

Review article written by Lukas Cajanek (our department) , Vitezslav Bryja (MU, Faculty of Science), and Igor Cervenka (Karolinska Institute, Sweden), entitled: The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic? was accepted in Critical Reviews in Biochemistry and Molecular Biology. Wnt signaling cascade has developed together with Read more about Review on centrosomes, cell cycle, and Wnt signaling[…]