September 10, 2019

Jan Křivánek

 Research interest | Team | Funding | Educational activities | Positions | Publications

jan_krivanekJan Krivanek, PhD, MSc

Assistant professor



Phone                  +420 549 49 5112


Research interest

The general focus of our group is driven by our curiosity of how tissues acquire their final shape, structure or function and how they maintain the homeostasis during a lifetime.
We primarily focus on a variety of different aspects of tooth growth, regeneration, reparation, physiology and microstructure mostly using specifically genetically modified mice, but we also use the acquired knowledge from model organisms in the study of potentials in human regenerative medicine.




Josef Lavicky, MSc

(PhD student)

PhD talent JCMM awarded




Vendula Fridrichova, DDS

(PhD student)





Adam Bogdanovic

(Bachelor student)




00-02_bVladislav Rakultsev

(Bachelor student)





Magdalena Kolouskova

(High school student)





Educational activities

Oral histology and embryology course (Faculty of Medicine, Masaryk University)



We are currently looking for motivated bachelor and master students with an interest in developmental biology willing to join a growing team of nice and friendly people, happy to work on interesting topics and participate in international collaborations.



  • GAMU High risk/High gain individual research project: Understanding of tooth developmental trajectories as a novel approach for dental regeneration, 2019-2022. (PI)
  • Institutional support by Faculty of Medicine MU for junior researchers (2018, PI)
  • Support for high school student projects, SOC – JCMM (2019)
  • PhD talent JCMM award for Josef Lavicky, MSc (2020-2023)


Selected publications

  • Vijaykumar, A., Ghassem-Zadeh, S., Vidovic-Zdrilic, I., Komitas, K., Adameyko, I., Krivanek, J., Fu, A., Maye, P., Mina, M. Generation and Characterization of DSPP-Cerulean/DMP1-Cherry reporter mice. Genesis. Jul 4:e23324.
  • Krivanek, J., Adameyko, I., Fried, K. Heterogeneity and Developmental Connections between Cell Types Inhabiting Teeth. Front Physiol. Jun 7; 8:376.
  • Li, L., Newton, P. T., Bouderlique, T., Sejnohova, M., Zikmund, T., Kozhemyakina, E., Xie, M., Krivanek, J., Kaiser, J., Qian, H., Dyachuk, V., Lassar, A. B., Warman, M. L., Barenius, B., Adameyko, I., Chagin, A. S. Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice. FASEB J. Mar; 31(3):1067-1084.
  • Khatibi Shahidi, M.*, Krivanek, J.*, Kaukua, N., Ernfors, P., Hladik, L, Kostal, V., Masich, S., Hampl, A., Chubanov, V., Gudermann, T., Romanov, R. A., Harkany, T., Adameyko, I., Fried, K. Three-dimensional Imaging Reveals New Compartments and Structural Adaptations in Odontoblasts. J Dent Res. 2015 Jul; 94(7):945-54. doi: 10.1177/0022034515580796. Epub 2015 Apr 2.                               * Equally contributing authors
  • Vinarsky, V., Krivanek, J., Rankel, L., Nahacka, Z., Barta, T., Jaros, J., Andera, L., Hampl, A. Human embryonic and induced pluripotent stem cells express TRAIL receptors and can be sensitized to TRAIL-induced apoptosis. Stem Cells Dev.22 (22): 2964-74.