- Registration deadline 31.8.2020
Get Together With Stem Cell Scientists
8.-9. October 2020
Important deadlines: Abstract submission 31.8.2020, Abstract decision 7.9.2020
Bon-Kyoung Koo – KEYNOTE SPEAKER
KEYNOTE SPEAKER - Institute of Molecular Biotechnology, Vienna, A
His research group focuses on homeostatic regulation of stem cells, particularly on gastro-intestinal stem cells. "We are learning that regeneration is tightly controlled by complex molecular signals. Specifically, negative feedback regulation via post-translational control of proteins plays a crucial role in maintaining adult tissue integrity as well as adult stem cell activity. "
Alexander W. Bruce
University of South Bohemia in České Budějovice, Faculty of Science, CZ
His group is concerned with uncovering the molecular basis of mechanisms of cell lineage derivation during the preimplantation developmental period of mammalian embryos, primarily utilising the mouse model. Specifically, how the blastomeres of the developing conceptus resist differentiation to retain their pluripotentcy and ultimately contribute to the epiblast, or differentiate into the supportive extra embryonic tissues of the trophectoderm and primitive endoderm, by the peri-implantation blastocyst stage. His lab also has an interest in molecular processes underlying meiotic maturation of primary oocytes.
International Clinical Research Center, Masaryk University, CZ
The Stem Cell and Disease Modeling research group (SCDM) builds on long term experience with human pluripotent stem cells, their cultivation and differentiation. Current focus of the group aims at use of human pluripotent stem cells to model human diseases which lead to cardiomyopathy and heart failure with special focus on progressive cardiomyopathies caused by cardiac progenitor depletion and heart remodeling due to cardiac progenitor genome instability. The SCDM uses reprogrammed human patient cells as well as human embryonic stem cells with edited genome to create models of monogenic diseases involving cardiomyopathy. The group also complements stem cell based modeling by analysis of both, animal models and human samples. The SCDM team has also developed novel technology to analyze mechanoelectrical coupling in stem cell derived patient specific cardiac syncytium based on atomic force microscope.
International Clinical Research Center, CZ