His group is concerned with uncovering the molecular basis of mechanisms of cell lineage derivation during the preimplantation developmental period of mammalian embryos, primarily utilising the mouse model. Specifically, how the blastomeres of the developing conceptus resist differentiation to retain their pluripotentcy and ultimately contribute to the epiblast, or differentiate into the supportive extra embryonic tissues of the trophectoderm and primitive endoderm, by the peri-implantation blastocyst stage. His lab also has an interest in molecular processes underlying meiotic maturation of primary oocytes.
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