Bon-Kyoung Koo

Bon-Kyoung Koo – keynote speaker – his research group focuses on homeostatic regulation of stem cells, particularly on gastro-intestinal stem cells.

His research adresses important questions:

  • How do adult tissue stem cells regulate the ratio between stem cells and specialized, differentiated cells during homeostasis?
  • How do adult tissue stem cells respond to tissue damage and restore homeostasis?

We are learning that regeneration is tightly controlled by complex molecular signals.  Specifically, negative feedback regulation via post-translational control of proteins plays a crucial role in maintaining adult tissue integrity as well as adult stem cell activity.

By studying the cellular and molecular behaviour of intestinal and gastric adult stem cells during homeostasis and following injury repair, we hope to answer these outstanding questions.

Lab webpages: https://www.imba.oeaw.ac.at/research/bon-kyoung-koo/